GSK J5

CAS No. 1394854-51-3

GSK J5( —— )

Catalog No. M33860 CAS No. 1394854-51-3

GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 59 Get Quote
5MG 122 Get Quote
10MG 202 Get Quote
25MG 434 Get Quote
50MG 634 Get Quote
100MG 885 Get Quote
500MG 1773 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GSK J5
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK J5 is an inhibitor of schistosomes and helminths and is often used as a trematode insecticide.GSK J5 promotes schistosome mortality in a dose- and time-dependent manner.
  • Description
    GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    Histone Demethylase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1394854-51-3
  • Formula Weight
    417.5
  • Molecular Formula
    C24H27N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (299.40 mM; Ultrasonic )
  • SMILES
    N(CCC(OCC)=O)C1=CC(=NC(=N1)C=2C=CC=NC2)N3CCC=4C(CC3)=CC=CC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kruidenier L, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 2012 Aug 16;488(7411):404-8.?
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